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ターゲット

203

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T1224	Cefuroxime sodium	Anaptivan,Cefuroxime sodium salt,Biociclin	Antibacterial , Antibiotic
	Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefuroxime sodium (Cefuroxime...		Antibacterial , Antibiotic
T22269	Benzyldodecyldimethylammonium Chloride Dihydrate		Antibacterial
	Benzyldodecyldimethylammonium chloride dihydrate can be used as an insecticide reagent. It can target drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, multidrug-resistant Pseudomonas aerugino...		Antibacterial
T8507	MAC-545496		Antibacterial
	MAC-545496 is a glycopeptide-resistance-associated protein R (GraR) inhibitor, is an antivirulence agent.		Antibacterial
T19794	Temafloxacin	Omniflox	Antibiotic
	Temafloxacin (Omniflox) is an antibiotic and antimycobacterial agent. It used to treat lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.		Antibiotic
T1031	Cloxacillin sodium monohydrate	Cloxacillin Sodium,Bactopen	Antibacterial , Antibiotic
	Cloxacillin sodium monohydrate (Cloxacillin Sodium) is the sodium salt of cloxaclliin, a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity.		Antibacterial , Antibiotic
T7804	Garenoxacin mesylate hydrate	Garenoxacin mesylate [USAN],BMS284756 (Mesylate hydrate)	Antibacterial
	Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains.		Antibacterial
T1389	Dyclonine hydrochloride	Dyclocaine hydrochloride,Dyclonine HCl	Sodium Channel , Antibacterial , Antifungal
	Dyclonine hydrochloride (Dyclonine HCl) , an over the counter throat lozenge, is found in Sucretswith local anesthetic effect .		Sodium Channel , Antibacterial , Antifungal
T0964	Floxuridine	5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640	Apoptosis , Nucleoside Antimetabolite/Analog , Others , DNA/RNA Synthesis , Antibacterial , HSV
	Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.
T1283	Clinafloxacin	PD 127391,CI-960,AM-1091	Antibacterial , Antibiotic
	Clinafloxacin (CI-960)(PD-127391) is a fluoroquinolone antibiotic.		Antibacterial , Antibiotic
T1293	Gatifloxacin	BMS 206584-01,PD 135432,CG5501,BMS-206584,AM-1155	Topoisomerase , Antibacterial , Antibiotic
	Gatifloxacin (CG5501) is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.		Topoisomerase , Antibacterial , Antibiotic
T7179	Garenoxacin	BMS284756	Antibacterial
	Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.		Antibacterial
T64316	VP-4604	1-((4-Nitrophenyl)sulfonyl)piperidine
	VP-4604 is a potent anti-methicillin-resistant Staphylococcus aureus (MRSA) compound. VP-4604 exhibited significant microbial growth inhibition against S. aureus with an MIC of 4-8 μg/mL. VP-4604 inhibited the growth of ...
T12126	MUT056399	Fab-001	Antibacterial
	MUT056399 (Fab-001) is a highly potent inhibitor of the FabI enzyme of both S. aureus and E. coli (IC50s of 12 nM and 58 nM, respectively).		Antibacterial
TQ0063	Zoliflodacin	ETX0914,AZD0914	DNA gyrase , DNA/RNA Synthesis , Topoisomerase , Antibacterial
	Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aur...
T4208	Targocil		Antibacterial
	Targocil is used as a bacteriostatic inhibitor of wall teichoic acid (WTA) biosynthesis which can inhibit the growth of methicillin-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA) (MIC90s: 2 μg/ m...		Antibacterial
T22387	NSC 55655	5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione	Others
	NSC 55655 (5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione) possesses antimicrobial and antioxidant activities and inhibits the proliferation of B. subtilis, S. aureus, K. pneumonia, E. coli, S. typhi , A. niger and C...		Others
T20936	Lauramine oxide	LDAO,Dimethylaurylamine oxide,Refan,Lauryldimethylamine oxide	Antibacterial
	Lauramine oxide (Refan) is effective against common bacteria such as E. coli and S. aureus, however it is non-denaturing and may be used to solubilize proteins.		Antibacterial
T61159	Antibacterial agent 26		Antibacterial
	Antibacterial agent 26 is an antimicrobial compound that is a potent DHFR inhibitor (S. aureus DHFR Ki of 0.020 nM).		Antibacterial
TP1663L	CysHHC10 acetate	CysHHC10 acetate(1408311-03-4 free base)	Antibacterial
	CysHHC10 acetate shows antibacterial activities against both Gram-positive and Gram-negative bacteria with MIC of 10.1, 20.2, 2.5, and 1.3 mM for E. coli, P. aeruginosa, S. aureus, and S. epidermidis, respectively.		Antibacterial
T6638	Retapamulin	SB-275833	ribosome , Antibacterial , Antibiotic
	Retapamulin (SB-275833), a Pleuromutilin Antibacterial, binds to both E. coli and S. aureus ribosomes with similar potencies (Kd: 3 nM).		ribosome , Antibacterial , Antibiotic
TQ0113	Iclaprim	AR-100	Antibacterial , Antibiotic
	Iclaprim (AR-100) is a novel specific bacterial Dihydrofolate inhibitor. It can inhibit the growth of S. aureus (MIC90: 0.06 μg/mL).		Antibacterial , Antibiotic
T28229	Olanexidine hydrochloride	OPB2045,OPB-2045,OPB-2045 HCl,OPB 2045	Antibacterial
	Olanexidine hydrochloride (OPB-2045 HCl) shows bactericidal activity against Gram-positive and Gram-negative bacteria. Olanexidine hydrochloride disrupts the membrane integrity of S. aureus.		Antibacterial
T10586L	BPH-1358	NSC50460	Others , Antibacterial
	BPH-1358 (NSC-50460) (NSC-50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 μM and 110 nM, respectively. And it is active against S. a...		Others , Antibacterial
TN6672	Cyclo(L-Phe-L-Pro)		Free radical scavengers , COX , Antibacterial , Antifungal
	Cyclo(L-Phe-L-Pro) shows broad-spectrum antibacterial and antifungal activities. Cyclo(L-Phe-L-Pro) exhibits activity against methicillin-resistant S. aureus and Enterococcus raffinosus.		Free radical scavengers , COX , Antibacterial , Antifungal
TP1412	RNAIII-inhibiting peptide TFA	RNAIII-inhibiting peptide(TFA)	Antibacterial
	RNAIII-inhibiting peptide TFA (RNAIII-inhibiting peptide(TFA))(228544-21-6 free base) inhibits S. aureus, effective in the diseases such as cellulitis, keratitis, septic arthritis, osteomylitis and mastitis.		Antibacterial
T19642	Nilofabicin	CG 0549,CG-0549,CG-400549,CG 400549,CG0549,CG400549	Antibacterial
	Nilofabicin (CG-400549) is a potent inhibitor of enoyl-(acyl-carrier-protein) reductase fall(FabI) and can be used in studies about the treatment of complicated acute.		Antibacterial
TP1773L	PGLa acetate		Antibacterial , Antibiotic
	PGLa acetate is a 21-residue member of the magainin family of antibiotic peptides.		Antibacterial , Antibiotic
T21358	Dalbavancin	BI 397,BI-397,VER 001,A-A 1,BI397,VER-001,Dalbavancin HCl	Antibacterial , Antibiotic
	Dalbavancin (BI-397), a novel second-generation lipoglycopeptide antibiotic, possesses in vitro activity against a variety of Gram-positive pathogens including methicillin-resistant Staphylococcus aureus (MRSA) and methi...		Antibacterial , Antibiotic
T2331	Solithromycin	OP-1068,CEM-101	Antibacterial , Antibiotic
	Solithromycin (OP-1068) is an orally bioavailable antimicrobial agent that inhibits cell viability, protein synthesis, and growth rate of Streptococcus pneumoniae, Staphylococcus aureus, Staphylococcus aureus, and Haemop...		Antibacterial , Antibiotic
T10587	BPH-652		Others
	BPH-652 is an S. aureus dehydrosqualene synthase (CrtM) inhibitor (Ki: 1.5 nM; IC50: 100-300 nM for S. aureus pigment formation).		Others
T72330	Antibacterial agent 19
	Antibacterial agent 19 exhibits strong activity against K. pneumoniae, (M-R) S. aureus, and (M-R,V-R) S. aureus, demonstrating minimum inhibitory concentrations (MICs) of 0.022 mg/mL for both K. pneumoniae and (M-R) S. a...
T76658	SYNV-cyclo(CGGYF)
	SYNV-cyclo(CGGYF), a C5 autoinducing peptide from Staphylococcus hominis (S. hominis), demonstrates inhibitory effects on Staphylococcus aureus (S. aureus) activity. This compound shows promise in research focused on add...
T76658L	SYNV-cyclo(CGGYF) TFA
	SYNV-cyclo(CGGYF) TFA, a C5 autoinducing peptide derived from Staphylococcus hominis (S. hominis), demonstrates inhibition of S. aureus activity, holding potential for research into S. aureus-mediated epithelial damage a...
T36594	4-Chloroguaiacol
	4-Chloroguaiaco (4-Chloro-2-methoxyphenol), a derivative of phenol, demonstrates antimicrobial efficacy, inhibiting Staphylococcus aureus and Escherichia coli with minimum inhibitory concentrations (MICs) of 110 μg/mL fo...
T80293	RP-1
	RP-1, an antimicrobial peptide, exhibits activity against a range of pathogens, including S. aureus, S. typhimurium, E. coli, and C. albicans [1].
T70386	QZN34
	QZN34 is a PqsR inhibitor which prevents S. aureus biofilm formation, severely damaged established S. aureus biofilms, and perturbed P. aeruginosa biofilm development. The mechanism of action of QZN 34 toward Gram-positi...
T36032	Desotamide
	Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces. It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs = 16, 12.5, and 32 μg/ml, respectiv...
T80047	Polistes mastoparan
	Polistes mastoparan, an antimicrobial peptide, enhances K+ efflux in S. aureus cells and reduces cell viability, exhibiting an EC50 of 5 μM [1].
T61911	Antibacterial agent 98
	Antibacterial agent 98 (compound g37) is an effective oral antibacterial agent, which can inhibit the ATPase activity of Gyrase B and weaken the DNA super-helix of S. aureus. Antibacterial agent 98 does not induce the de...
T77111	Omodenbamab
	Omodenbamab, a humanized monoclonal antibody targeting Staphylococcal protein A (SpA), exhibits a dissociation constant (K D) of 0.0467 nM, effectively countering a crucial S. aureus evasion strategy by focusing on the c...
T70798	Benastatin B
	Benastatin B is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; Ki = 3.7 µM for the rat liver enzyme).2 Bena...
T64069	Antibacterial agent 87
	Antibacterial agent 87 is an effective antibacterial agent that acts on MRSA (MIC: 0.125 μg/ml), MRSE (MIC: 0.0625 μg/ml) and S. aureus (MIC: 0.0625 μg/ml).
T27389	Frequentin
	Frequentin, an antibiotic originally isolated from P. frequentans, is active against bacteria (MICs = 200 and 300 µg/ml for B. subtilis and S. aureus, respectively) and fungi.
T38334	Corynecin III
	Corynecin III is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It inhibits the growth of Gram-positive and Gram-negative bacteria, including S. faecalis, S. aureus, B. subtilis, E. coli, P. ...
T38333	Corynecin I
	Corynecin I is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It is active against Gram-positive and Gram-negative bacteria with MIC values of 5.2-83 μg/ml for S. sonnei, P. vulgaris, K. pneu...
T38102	Decatromicin B
	Decatromicin B is a bacterial metabolite that has been found in Actinomadura. It is active against Gram-positive bacteria, including several strains of S. aureus (MICs = 0.39-0.78 μg/ml), two strains of methicillin-resis...
T80300	Aurein 2.6		Antibiotic
	Aurein 2.6, an antibiotic antimicrobial peptide, exhibits activity against various Gram-positive bacteria with minimum inhibitory concentrations (MIC) of 25, 25, 30, 25, and 30 μM for M. luteus, S. aureus, S. epidermis, ...		Antibiotic
T80301	Aurein 3.1		Antibiotic
	Aurein 3.1 is an antibiotic antimicrobial peptide, whereas Aurein 2.6 demonstrates activity against Gram-positive bacteria, exhibiting minimum inhibitory concentrations (MIC) of 80 μM for M. luteus and 50 μM for S. aureu...		Antibiotic
T37914	Pipacycline
	Pipacycline is a tetracycline antibiotic derivative. It inhibits the formation of penicillinase, the enzyme that inactivates penicillin in bacteria. It decreases oxygen uptake and inhibits growth of penicillin-resistant ...
T38290	Leucomycin A4	Leucomycin A4
	Leucomycin A4 is a macrolide antibiotic that has been found in S. kitasatoensis. It is active against a variety of bacteria, including S. aureus, B. subtilis, C. diphtheriae, N. gonorrhoeae, and H. influenzae (MICs = 0.1...

Compounds

Cefuroxime sodium

T1224

Synonym: Anaptivan,Cefuroxime sodium salt,Biociclin

Target: Antibacterial, Antibiotic

Benzyldodecyldimethylammonium Chloride Dihydrate

T22269

Synonym:

Target: Antibacterial

MAC-545496

T8507

Synonym:

Target: Antibacterial

Cloxacillin sodium monohydrate

T1031

Synonym: Cloxacillin Sodium,Bactopen

Target: Antibacterial, Antibiotic

Garenoxacin mesylate hydrate

T7804

Synonym: Garenoxacin mesylate [USAN],BMS284756 (Mesylate hydrate)

Target: Antibacterial

Dyclonine hydrochloride

T1389

Synonym: Dyclocaine hydrochloride,Dyclonine HCl

Target: Sodium Channel, Antibacterial, Antifungal

Floxuridine

T0964

Synonym: 5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640

Target: Apoptosis, Nucleoside Antimetabolite/Analog, Others, DNA/RNA Synthesis, Antibacterial, HSV

Clinafloxacin

T1283

Synonym: PD 127391,CI-960,AM-1091

Target: Antibacterial, Antibiotic

Gatifloxacin

T1293

Synonym: BMS 206584-01,PD 135432,CG5501,BMS-206584,AM-1155

Target: Topoisomerase, Antibacterial, Antibiotic

Garenoxacin

T7179

Synonym: BMS284756

Target: Antibacterial

VP-4604

T64316

Synonym: 1-((4-Nitrophenyl)sulfonyl)piperidine

Target: Antibacterial

Zoliflodacin

TQ0063

Synonym: ETX0914,AZD0914

Target: DNA gyrase, DNA/RNA Synthesis, Topoisomerase, Antibacterial

Targocil

T4208

Synonym:

Target: Antibacterial

NSC 55655

T22387

Synonym: 5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione

Target: Others

Lauramine oxide

T20936

Synonym: LDAO,Dimethylaurylamine oxide,Refan,Lauryldimethylamine oxide

Target: Antibacterial

Antibacterial agent 26

T61159

Synonym:

Target: Antibacterial

CysHHC10 acetate

TP1663L

Synonym: CysHHC10 acetate(1408311-03-4 free base)

Target: Antibacterial

Retapamulin

T6638

Synonym: SB-275833

Target: ribosome, Antibacterial, Antibiotic

Iclaprim

TQ0113

Synonym: AR-100

Target: Antibacterial, Antibiotic

Olanexidine hydrochloride

T28229

Synonym: OPB2045,OPB-2045,OPB-2045 HCl,OPB 2045

Target: Antibacterial

BPH-1358

T10586L

Synonym: NSC50460

Target: Others, Antibacterial

Cyclo(L-Phe-L-Pro)

TN6672

Synonym:

Target: Free radical scavengers, COX, Antibacterial, Antifungal

RNAIII-inhibiting peptide TFA

TP1412

Synonym: RNAIII-inhibiting peptide(TFA)

Target: Antibacterial

Nilofabicin

T19642

Synonym: CG 0549,CG-0549,CG-400549,CG 400549,CG0549,CG400549

Target: Antibacterial

PGLa acetate

TP1773L

Synonym:

Target: Antibacterial, Antibiotic

Dalbavancin

T21358

Synonym: BI 397,BI-397,VER 001,A-A 1,BI397,VER-001,Dalbavancin HCl

Target: Antibacterial, Antibiotic

Solithromycin

T2331

Synonym: OP-1068,CEM-101

Target: Antibacterial, Antibiotic

Antibacterial agent 19

SYNV-cyclo(CGGYF) TFA

Antibacterial agent 98

Antibacterial agent 87

Synonym: Leucomycin A4

Target:

カタログ番号	製品名	別名	ターゲット
T5780	HYPOCRELLIN B		Apoptosis , Parasite , Antifungal
	HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage, induces apoptosis in ovarian cancer cells, and inhibits proliferation of Staphylococcus by incre...		Apoptosis , Parasite , Antifungal
T3381	Lysionotin		Others
	Lysionotin (Nevadensin) has expectorant, eliminating phlegm, softening effects.		Others
T5802	Stearyl glycyrrhetinate		Antiviral , Antibacterial
	Stearyl glycyrrhetinate, the stearyl ester of 18-β-glycyrrhetinic acid, has been demonstrated to improve antiviral effects, reduce inflammation and suppress allergies in the pharmaceutical and cosmetic industry.		Antiviral , Antibacterial
TN2730	2,5-Dihydroxybenzaldehyde	Gentisaldehyde	Anti-infection , Antibacterial
	2,5-Dihydroxybenzaldehyde (Gentisaldehyde) has antioxidant activity against Mycobacterium avium subsp. Paratuberculosis. 2,5-Dihydroxybenzaldehyde also inhibits S. aureus strains(MIC50: 500 mg/L).		Anti-infection , Antibacterial
T1126	Penicillin V Potassium	Penicillin V potassium salt,Phenoxymethylpenicillin potassium salt	Antibacterial , Antibiotic
	Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is a broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.		Antibacterial , Antibiotic
T8384	Gatifloxacin hydrochloride	AM-1155 (hydrochloride),BMS-206584 (hydrochloride),PD135432 (hydrochloride)	Topoisomerase , Antibacterial , Antibiotic
	Gatifloxacin hydrochloride (AM-1155 hydrochloride) is an antibiotic of the fourth-generation fluoroquinolone family, which can inhibit the bacterial enzyme DNA rotase and topoisomerase IV.		Topoisomerase , Antibacterial , Antibiotic
T13708	Glycol chitosan		Antibacterial
	Glycol chitosan is a chitosan derivative with hydrophilic ethylene glycol branches. Glycol chitosan inhibits E. coli, S. aureus, and S. enteritidis growths (MICs: 4 μg/mL, 32 μg/mL, and <0.5 μg/mL). It enhances membrane ...		Antibacterial
T37753	Aureusimine B		Cysteine Protease , Antibacterial
	Aureusimine B, also known as phevalin, is a natural pyrazinone produced by certain fungi and by Staphylococcus spp., including S. aureus. Its synthesis appears to be initiated by a conserved nonribosomal peptide syntheta...		Cysteine Protease , Antibacterial
TN1524	Continentalic acid		NOS , COX , Antibacterial , Prostaglandin Receptor
	Continentalic acid from Aralia continentalis has minimum inhibitory concentrations (MICs) of approximately 8-16 µg/mL against S. aureus, including the Methicillin-resistant Staphylococcus aureus (MRSA) and Methicillin su...		NOS , COX , Antibacterial , Prostaglandin Receptor
TN7094	Coreoside B		Antibacterial
	Coreoside B is isolated from coreoside and showed weak antimicrobial activity against S. aureus and B. anthracis.		Antibacterial
T37267	Pachybasin		Antibacterial
	Pachybasin is an anthraquinone fungal metabolite. Pachybasin shows antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and...		Antibacterial
TN2281	Sinapaldehyde	trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde	Antibacterial
	Sinapaldehyde (trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde) is a natural product. Sinapaldehyde exhibits moderate antibacterial against Methicillin resistant S. aureus (MRSA) and E. coli with MIC values of 128 and 128 μ...		Antibacterial
TN1949	Moracin C		ROS , NO Synthase
	Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release and LPS-activated reactive oxygen species (ROS) in cells.		ROS , NO Synthase
TN2898	Kaempferol-7,4'-dimethyl ether	3,5-Dihydroxy-4',7-dimethoxyflavone	Antioxidant , Antifection
			Antioxidant , Antifection
T6S0525	Farrerol		ERK , p38 MAPK , Akt
	1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3....		ERK , p38 MAPK , Akt
T13305	Viridicatol		Anti-infection , Antifungal
	Viridicatol, with potent antibacterial activity against Staphylococcus aureus(MIC: 15.6 μg/mL), is isolated from the fermentation of an endophytic fungus Penicillium sp. R22 in Nerium indicum.		Anti-infection , Antifungal
TN2447	Isovalerylshikonin		Antibacterial
	Isovalerylshikonin is a natural product from Arnebia euchroma		Antibacterial
T5S1981	Alpha-Cyperone	(+)-α-Cyperone,α-Cyperone	Others , Endogenous Metabolite
	1. alpha-Cyperone (α-Cyperone) is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. alpha-Cyperone significantly inhibited PGE2 production by suppressing the LPS-induced...		Others , Endogenous Metabolite
TN1722	Hamamelitannin		Antifection
	Hamamelitannin has cytotoxic, and antibiofilm activities. It increases the susceptibility of S. aureus to antibiotic treatment in in vivo Caenorhabditis elegans and mouse mammary gland infection models. It also has a hig...		Antifection
T6873	Lauric Acid	Dodecylic acid,dodecanoic acid,Vulvic acid,N-Dodecanoic acid	Others , Endogenous Metabolite , Antibacterial
	Lauric Acid (Dodecylic acid),which is found naturally in various plant and animal fats and oils, is a saturated medium-chain fatty acid with a 12-carbon backbone. It is a major component of coconut oil and palm kernel oi...		Others , Endogenous Metabolite , Antibacterial
TN3861	Dihydropinosylvin		Anti-infection
	Dihydropinosylvinin is an phytoalexin, it shows antifungal activity against Cladosporium cladosporioides, Botryodiplodia theobromae, Aspergillus niger and Penicillium schlerotgenum, it also exhibits strong antibacterial ...		Anti-infection
TC0017	Haplopine		Tyrosinase , Antifection
	Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the cells.		Tyrosinase , Antifection
T72805	(±)-Hydnocarpin
	(±)-Hydnocarpin, a flavonolignan, demonstrates inhibitory activity against S. aureus growth, exhibiting a minimum inhibitory concentration (MIC) value of 3.1 μM.
T27024	Citromycetin	Frequentic Acid,NSC-53584,NSC 53584,NSC53584
	Citromycetin is a fungal metabolite originally isolated from Australian P. frequentans. It has antibiotic activity against the Gram-negative bacteria V. cholerae and S. flexneri and the Gram-positive bacteria S. aureus.
TN3216	(3R)-7,4’-Dihydrohomoisoflavanone	7,4'-Dihydroxyhomoisoflavanone	Antibacterial
	(3R)-7,4’-Dihydrohomoisoflavanone, a natural compound, exhibits potent antibacterial properties against both S. aureus and methicillin-resistant Staphylococcus aureus (MRSA).		Antibacterial
TN2809	22-Dehydroclerosterol		Antifection
	22-Dehydroclerosterol has antibacterial activity against against E. coli, S. aureus, and H. pylori.		Antifection
TN4725	Oxychelerythrine		Antifection
	Oxychelerythrine shows high modulatory activity enhancing the susceptibility of the S. aureus ATCC 6538 to all the tested antibiotics from two to four-fold. It also shows antifeeding activities against Tribolium castaneu...		Antifection
TN1526	Corydalmine		P450 , Antifection
	Corydalmine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains.1-Corydalmine significantly inhibits spore germination of all the fungi at 100 to 1500 ppm. l-Coryda...		P450 , Antifection
T36417	Nargenicin	Antibiotic 47444
	Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg/ml, respectively) over a panel of 11 Gram-positive...
T35754	Aszonapyrone A
	Aszonapyrone A is a meroditerpene fungal metabolite that has been found in Neosartorya and has diverse biological activities.1,2,3 It inhibits the growth of MCF-7, NCI H460, and A375-C5 cancer cells (GI50s = 13.6, 11.6, ...
TN3978	Epitaraxerol		Antifection
	Epitaraxerol shows moderate antifungal activity against C. albicans and low antimicrobial activity against T. mentagrophytes, A. niger, S. aureus, E. coli, P. aeruginosa, and B. subtilis.		Antifection
T69058	OM173-αA
	OM173-αA is a quinone bacterial metabolite that inhibits the growth of the bacteria M. gallisepticum, M. pneumoniae, and S. aureus. OM173-αA also inhibits the growth of the plant pathogenic fungus P. oryzae and several s...
TN3573	Camaric acid		Antifection
	Camaric acid shows antibacterial activity against Staphylococcus aureus and methicillin resistant S. aureus with IC50 values 8.74 and 8.09 uM, respectively, it also shows moderate antileishmanial activity and highly pote...		Antifection
TN6010	Picrasidine S
	Picrasidine S shows the potent cytotoxicity against human HeLa cervical, gastric MKN-28, and mouse melanoma B-16 cancer cells, it also shows the potent antibacterial activity against two strains of pathogenic bacteria me...
T83862	Bactobolin A hydrochloride	BN-183B
	Bactobolin A, a microbial metabolite initially derived from Pseudomonas, exhibits both antibiotic and anticancer properties. It demonstrates activity against various bacteria including S. aureus, S. epidermidis, S. faeca...
T36044	17-hydroxy Venturicidin A
	17-hydroxy Venturicidin A is a macrolide fungal metabolite originally isolated from Streptomyces. It has antibiotic activity against M. luteus, B. subtilis, and S. aureus and antifungal activity against V. dahlia, Fusari...
T83918	Clazamycin A hydrochloride	NSC 332188
	Clazamycin A, a microbial metabolite and antibiotic derived from Streptomyces, exhibits efficacy against several bacteria, namely S. aureus, B. anthracis, B. subtilis, E. coli, and P. aeruginosa, with minimum inhibitory ...
T38086	Neohydroxyaspergillic Acid
	Neohydroxyaspergillic acid is a fungal metabolite produced by A. sclerotiorum that has antibiotic and antifungal activities. It inhibits the growth of P. aeruginosa, M. smegmatis, S. aureus, E. coli, K. pneumoniae, B. my...
TN3404	Altholactone		BCL , p38 MAPK , ROS , Akt , Caspase , Antifection , p53
	Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections. It can inhibit the growth of various types of cancer cells through inducing apoptosis vi...		BCL , p38 MAPK , ROS , Akt , Caspase , Antifection , p53
TN5404	(+)-Conocarpan
	Conocarpan has antinociceptive effects. Conocarpan is quite active against S. aureus and B. subtilis with MIC of 6.25 micrograms/ml, it also shows activity against M. tuberculosis (MIC=15.6 ug/ml). Conocarpan shows consi...
TN5466	Boeravinone B
	Boeravinone B, a novel efflux pump inhibitor, apart from inhibiting the MdeA mediated efflux, also significantly inhibit the biofilm formation of S. aureus, boeravinone B may be used in combination with mupirocin for fur...
TN4319	Isopimaric acid		Antifection
	Isopimaric acid is active against MDR and MRSA strains of S. aureus which are becoming increasingly resistant to antibiotics, the minimum inhibitory concentrations (MIC) are 32-64 microg/mL . Isopimaric acid is also poss...		Antifection
T37442	Aspergillin PZ
	Aspergillin PZ is a fungal metabolite originally isolated from A. awamori. It induces morphological deformation of P. oryzae conidia when used at a concentration of 89 nM. Aspergillin PZ is active against S. epidermidis ...
T38016	Hirsutide
	Hirsutide is a cyclotetrapeptide fungal metabolite produced by the entomopathogenic fungus Hirsutella. It has antibacterial activity against C. pyogenes, S. aureus, P. aeruginosa, and K. pneumonia (MICs = 25, 13, 6, and ...
TN4264	Isoapetalic acid		HIV Protease , Antifection
	Isoapetalic acid and apetalic acid exhibit cytotoxic activities towards both cancer cell lines(human breast cancer (MCF-7) and human lung carcinoma (A-549) cell lines) and both Gram-positive bacteria(two Gram-positive ba...		HIV Protease , Antifection
T72235	Antibacterial synergist 2
	Antibacterial synergist 2, functioning as a biofilm inhibitor, demonstrates inhibitory effects against pathogens such as S. enterica, S. aureus, P. aeruginosa, and C. albicans. This compound is applicable in research con...
T38097	Antibiotic PF 1052
	Antibiotic PF 1052 is a fungal metabolite originally isolated from Phoma.1,2 It is active against S. aureus, S. parvulus, and C. perfringens (MICs = 3.13, 0.78, and 0.39 μg/ml, respectively), among others.1 It inhibits n...
TN5014	Shoreic acid		Antifection , HSV
	Shoreic acid exhibits antibacterial activity against E. coli, P. aeruginosa, S. aureus, and B. subtilis with activity indices (AI) of 0.2, 0.3, 0.5 and 0.4, respectively, it also shows antifungal activity against C. albi...		Antifection , HSV
T75278	Pristinamycin
	Pristinamycin, synthesized by Streptomyces pristinaespiralis, is an orally administered antibiotic resembling streptogramin, comprising two distinct components: Pristinamycin I (PI) and Pristinamycin II (PII). This compo...
T80330	XT-1
	XT-1, an antimicrobial peptide sourced from Xenopus tropicalis skin secretions, exhibits potent activity against S. aureus, E. coli, and C. albicans, with minimum inhibitory concentration (MIC) values of 5, 6, and 50 μM,...
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天然物製品

HYPOCRELLIN B

T5780

Synonym:

Target: Apoptosis, Parasite, Antifungal

Stearyl glycyrrhetinate

T5802

Synonym:

Target: Antiviral, Antibacterial

2,5-Dihydroxybenzaldehyde

TN2730

Synonym: Gentisaldehyde

Target: Anti-infection, Antibacterial

Penicillin V Potassium

T1126

Synonym: Penicillin V potassium salt,Phenoxymethylpenicillin potassium salt

Target: Antibacterial, Antibiotic

Gatifloxacin hydrochloride

T8384

Synonym: AM-1155 (hydrochloride),BMS-206584 (hydrochloride),PD135432 (hydrochloride)

Target: Topoisomerase, Antibacterial, Antibiotic

Glycol chitosan

T13708

Synonym:

Target: Antibacterial

Aureusimine B

T37753

Synonym:

Target: Cysteine Protease, Antibacterial

Continentalic acid

TN1524

Synonym:

Target: NOS, COX, Antibacterial, Prostaglandin Receptor

Coreoside B

TN7094

Synonym:

Target: Antibacterial

Pachybasin

T37267

Synonym:

Target: Antibacterial

Sinapaldehyde

TN2281

Synonym: trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde

Target: Antibacterial

Moracin C

TN1949

Synonym:

Target: ROS, NO Synthase

Kaempferol-7,4'-dimethyl ether

TN2898

Synonym: 3,5-Dihydroxy-4',7-dimethoxyflavone

Target: Antioxidant, Antifection

Farrerol

T6S0525

Synonym:

Target: ERK, p38 MAPK, Akt

Viridicatol

T13305

Synonym:

Target: Anti-infection, Antifungal

Isovalerylshikonin

TN2447

Synonym:

Target: Antibacterial

alpha-Cyperone

T5S1981

Synonym: (+)-α-Cyperone,α-Cyperone

Target: Others, Endogenous Metabolite

Synonym: Dodecylic acid,dodecanoic acid,Vulvic acid,N-Dodecanoic acid

Target: Others, Endogenous Metabolite, Antibacterial

Dihydropinosylvin

TN3861

Synonym:

Target: Anti-infection

Haplopine

TC0017

Synonym:

Target: Tyrosinase, Antifection

Synonym: Frequentic Acid,NSC-53584,NSC 53584,NSC53584

Target:

(3R)-7,4’-Dihydrohomoisoflavanone

TN3216

Synonym: 7,4'-Dihydroxyhomoisoflavanone

Target: Antibacterial

22-Dehydroclerosterol

Target: P450, Antifection

Nargenicin

T36417

Synonym: Antibiotic 47444

Bactobolin A hydrochloride

T83862

Synonym: BN-183B

Target:

17-hydroxy Venturicidin A

T36044

Synonym:

Target:

Clazamycin A hydrochloride

T83918

Synonym: NSC 332188

Target:

Neohydroxyaspergillic Acid

Target: BCL, p38 MAPK, ROS, Akt, Caspase, Antifection, p53

Target: HIV Protease, Antifection

Antibacterial synergist 2

Target: Antifection, HSV

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-03563	MCAT Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	Yeast
	MCAT Protein, S. aureus, Recombinant (His) is expressed in Yeast with N-terminal 6xHis tag. The predicted molecular weight is 35.6 kDa. Accession number: Q5HGK3
TMPH-03525	Cap5A Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	in vitro E. coli expression system
	Required for the biosynthesis of type 5 capsular polysaccharide (Cap5/CP5). Might act as the chain-length regulator.
TMPH-03574	SdrE Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	E. coli
	Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis. Contributes to the resistance to killing by innate immune components in blood and thus attenuates bacterial clea...
TMPH-03519	ACP Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	Yeast
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced.
TMPH-03564	MCAT Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	MCAT Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli with N-terminal 6xHis-SUMO tag. The predicted molecular weight is 49.6 kDa. Accession number: Q5HGK3
TMPH-03520	ACP Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced.
TMPH-03560	LsdA Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Cell wall-anchored surface receptor that participates in the extraction of heme from oxidized methemoglobin/metHb to enable growth on hemoglobin as a sole iron source. Receives heme from IsdB and transfers it to IsdC. Pl...
TMPH-03572	SplB Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Serine protease that cleaves specifically after the sequence Trp-Glu-Leu-Gln.
TMPH-03515	ClfA Protein, S. aureus (strain MSSA476), Recombinant	Staphylococcus aureus	E. coli
	Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps.
TMPH-03557	HlgC Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	Yeast
	Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity.
TMPH-03527	FtsZ Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	E. coli
	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the fun...
TMPH-03558	LytM Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	E. coli
	Peptidoglycan hydrolase (autolysin) specifically acting on polyglycine interpeptide bridges of the cell wall peptidoglycan.
TMPH-03526	Cap8A Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	in vitro E. coli expression system
	May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate comp...
TMPH-03518	ACP Protein, S. aureus, Recombinant (GST)	Staphylococcus aureus	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced.
TMPH-03555	HlgB Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	Yeast
	Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity.
TMPH-03565	MazF Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	E. coli
	Toxic component of a type II toxin-antitoxin (TA) system. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. It cuts between the f...
TMPH-03573	SplD Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	SplD Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli with N-terminal 10xHis tag and C-terminal Myc tag. The predicted molecular weight is 29.5 kDa. Accession number: Q2FXC5
TMPH-03571	WalK Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Member of the two-component regulatory system WalK/WalR that regulates genes involved in cell wall metabolism, virulence regulation, biofilm production, oxidative stress resistance and antibiotic resistance via direct or...
TMPH-03578	SCIN Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a ...
TMPH-03533	Ddl Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Cell wall formation.
TMPH-03553	HlgA Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity.
TMPH-03550	EsxA Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Virulence factor that is important for the establishment of infection in the host. EsxA is required for EsxB synthesis as well as secretion. Modulates host cell apoptotic pathways and mediates together with EsxB the rele...
TMPH-03521	MecA Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
TMPH-03570	IsaA Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Is able to cleave peptidoglycan.
TMPH-03524	KAS III Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may ther...
TMPH-03567	Peptide deformylase Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has b...
TMPH-03531	ClfA Protein, S. aureus (strain COL), Recombinant (His)	Staphylococcus aureus	Yeast
	Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps.
TMPH-03539	Enterotoxin type B Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	Yeast
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPH-03577	Staphopain B Protein, S. aureus, Recombinant (GST)	Staphylococcus aureus	E. coli
	Cysteine protease that plays an important role in the inhibition of host innate immune response. Degrades host elastin, fibrogen, fibronectin and kininogen. Blocks phagocytosis of opsonised S. aureus by neutrophils and m...
TMPH-03516	NPTase Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Highly cationic enzyme that can bind human or rat immunoglobulins as well as serum albumin, and could therefore be involved in post-infectious sequelae.
TMPH-03568	Phospholipase C Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	Yeast
	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydr...
TMPH-03575	Sortase A Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	E. coli
	Transpeptidase that anchors surface proteins to the cell wall. Recognizes and modifies its substrate by proteolytic cleavage of a C-terminal sorting signal. Following cleavage, a covalent intermediate is formed via a thi...
TMPH-03561	LsdB Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Cell wall-anchored surface receptor that extracts heme from oxidized metHb to enable growth on hemoglobin as a sole iron source. Rapidly extracts heme from hemoglobin and transfers it to IsdA or IsdC, which then relays i...
TMPH-03536	FabI Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism.
TMPH-03522	Alpha-hemolysin Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	Yeast
	Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probabl...
TMPH-03566	Peptide deformylase Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	Yeast
	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has b...
TMPH-03569	IcaB Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. N-deacetylation is crucial for attachment of the polysaccharide to the bacterial ce...
TMPH-03556	HlgC Protein, S. aureus, Recombinant (E. coli, His)	Staphylococcus aureus	E. coli
	Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity.
TMPH-03549	Enterotoxin type H Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	Yeast
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules via their alpha domain, in parti...
TMPH-03544	Enterotoxin type D Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPH-03580	Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Plays an essential role in immune evasion by helping bacteria to resist complement-mediated killing by neutrophils. Inhibits the deposition of host C3b on bacterial surfaces and the release of the chemoattractant C5a by ...
TMPH-03552	Exfoliative toxin B Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Has serine protease-like properties and binds to the skin protein profilaggrin. Cleaves substrates after acidic residues. Exfoliative toxins cause impetigous diseases commonly referred as staphylococcal scalded skin synd...
TMPH-03529	Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Recombinant (His)	Staphylococcus aureus	Yeast
	Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leu...
TMPH-03579	TSST-1 Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Responsible for the symptoms of toxic shock syndrome.
TMPH-03534	Delta-hemolysin Protein, S. aureus, Recombinant (His & KSI)	Staphylococcus aureus	E. coli
	Lyses erythrocytes and many other mammalian cells.
TMPH-03523	Alpha-hemolysin Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probabl...
TMPH-03535	Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
TMPH-03537	Enterotoxin type A Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, waves of cellular acti...
TMPH-03551	Exfoliative toxin A Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	E. coli
	Has serine protease-like properties and binds to the skin protein profilaggrin. Cleaves substrates after acidic residues. Exfoliative toxins cause impetigous diseases commonly referred as staphylococcal scalded skin synd...
TMPH-03576	Staphopain A Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Cysteine protease that plays an important role in the inhibition of host innate immune response. Cleaves host elastins found in connective tissues, pulmonary surfactant protein A in the lungs, and the chemokine receptor ...
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